Analysis of Antimicrobial Activity of Titaniumdioxide Nanoparticles on Aerobic and Anaerobic Dental Isolates

Dental plaque is a biofilm or mass of bacteria that grows on surface within the mouth. It is a sticky colorless deposit at first, but when it forms tartar it is brown or pale yellow that is commonly found between the teeth, front of teeth, behind teeth, on chewing surface, along the gumline,. A study was carried out to isolate microorganisms from patients with dental problems. Total 8 dental plaque samples were collected from Savitha dental clinic, Hyderabad, which showed the presence of both aerobic and anaerobic bacteria. Titanium dioxide nanoparticle was synthesized and checked for its antimicrobial activity against dental plaque samples. TiO2 nanoparticles were then incorporated into some commercial toothpastes and checked against dental plaque causing organisms using commercial toothpaste as control. The activity was also checked using bulk TiO2. TiO2 nanoparticles incorporated into tooth paste showed enhanced activity compared to toothpaste alone. Antimicrobial activity of TiO2 synthesized by wet chemical method was compared against commercial TiO2 P23.It was observed that TiO2 nanoparticles synthesized by wet chemical method showed greater antimicrobial activity than commercial TiO2 nanoparticles and bulk oxide. Astringent mouthwash was prepared and TiO2 nanoaprticles were incorporated into it and the activity was compared.